疗效肯定。 神经生长因子治疗新生儿缺氧缺血性脑病疗效观察 薛 媛,尹晓娟△ ,晏 玲 (第三军医大学西南医凡密院儿科,重庆400038) 摘 要:目的 观察神经生长因子对新生儿缺氧缺血性脑病的疗效。方法 对照组患儿39 例及治疗组患儿47 例给予支持 治疗及对症治疗,同时治疗组患儿应用神经生长因子肌注10d。结果 对照组总有效率74. 4 % ,治疗组总有效率93. 6 %;治疗组 明显高于对照组,差异有统计学意义( P < 0. 05) 。结论 神经生长因子治疗新生儿缺氧缺血性脑病有怪剑明显疗效。 关键词:神经生长因子;治疗;缺氧缺血性脑病 中图分类号:R722. 1 文献标识码:A 文章编它崇挤号:167128348 (2006) 2222030202 Clinical observation of effects of nerve growth factor on management of hypoxic2ischemic encephalopathy XU E Yuan , Y I N Xiao2j uan , YA N L ing ( Department of Pediat rics , S outhwest Hos pi tal , Thi rd Mi l i tary Medical Uni versi t y , Chongqi ng 400038 , China) Abstract :Objective To investigate the clinical effect of nerve growth factor on the management of hypoxic2ischemic encepha2 lopathy ( HIE) . Methods Total eighty2six children with HIE were enrolled in the study and randomized into cont rol (39 ceses) and t reatment (47 cese) groups. The patient s in the two groups received routine supporting therapy. In addition , those in the t reat2 ment group received muscular injection of N GF for 10d. Results The efficacy in t reatment group was 93. 6 % , which was obviously higher than that in cont rol group (74. 4 % , P < 0. 05) . Conclusion Nerve growth factor is beneficial for the management of hypoxic2 ischemic encephalopathy. Key words :nerve growth factor ;therapy ;hypoxic2ischemic encephalopathy